3-Thiatetradecanoic Acid

3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels. Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Delta9-desaturase, and dose-dependently increases Delta9-desaturase mRNA levels.Formal Name: (undecylthio)-acetic acid. CAS Number: 116296-31-2. Synonyms: 3-TDA. Molecular Formula: C13H26O2S. Formula Weight: 246.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: Miscible, DMSO: 30 mg/ml, Ethanol: Miscible, Ethanol:PBS (pH 7.2) (1:3): 1 mg/ml. SMILES: CCCCCCCCCCCSCC(O)=O. InChi Code: InChI=1S/C13H26O2S/c1-2-3-4-5-6-7-8-9-10-11-16-12-13(14)15/h2-12H2,1H3,(H,14,15). InChi Key: CZSSKBQAJULWPY-UHFFFAOYSA-N.