2,3-dinor-8-iso Prostaglandin F2alpha

2,3-dinor-8-iso Prostaglandin F2alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16290-25 25 µg -

6 - 10 business days*

Cay16290-50 50 µg -

6 - 10 business days*

Cay16290-100 100 µg -

6 - 10 business days*

8-iso Prostaglandin F2alpha (8-iso PGF2alpha, 8-isoprostane) is a prostaglandin-like product of... more
Product information "2,3-dinor-8-iso Prostaglandin F2alpha"
8-iso Prostaglandin F2alpha (8-iso PGF2alpha, 8-isoprostane) is a prostaglandin-like product of non-specific lipid peroxidation. 2,3-dinor-8-iso PGF2alpha is a metabolite of 8-iso PGF2alpha in humans and rats. In these species, exogenously infused 8-iso PGF2alpha is converted to 2,3-dinor-8-iso PGF1alpha and (2,3-dinor-8-iso PGF2alpha. Rat hepatocytes further metabolize 8-iso PGF2alpha to another beta-oxidation product, 2,3,4,5-tetranor-8-iso PGF2alpha. 2,3-dinor-8-iso PGF2alpha is present in normal human urine at concentrations of 200-300 pg/ml. Its concentration is increased in conditions of oxidative injury (for example, smoking), and correlates well with that of the parent isoprostane, 8-iso PGF2alpha. Formal Name: 9alpha,11alpha,15S-trihydroxy-2,3-dinor-(8beta)-prosta-5Z,13E-dien-1-oic acid. CAS Number: 221664-05-7. Synonyms: 2,3-dinor-iPF2alpha-III, 2,3-dinor-8-iso PGF2alpha. Molecular Formula: C18H30O5. Formula Weight: 326.4. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[C@@H]1[C@@H](C/C=C\CC(O)=O)[C@@H](/C=C/[C@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C18H30O5/c1-2-3-4-7-13(19)10-11-15-14(16(20)12-17(15)21)8-5-6-9-18(22)23/h5-6,10-11,13-17,19-21H,2-4,7-9,12H2,1H3,(H,22,23)/b6-5-,11-10+/t13-,14-,15+,16-,17+/m0/s1. InChi Key: IDKLJIUIJUVJNR-JSEKUSAISA-N.
Keywords: 2,3-dinor-8-iso PGF2alpha, 2,3-dinor-iPF2alpha-III, 9alpha,11alpha,15S-trihydroxy-2,3-dinor-(8beta)-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 16290


Application: Bioactive lipid assays
MW: 326.4 D
Formula: C18H30O5
Purity: >98%
Format: Solution

Database Information

CAS : 221664-05-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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