2,3-dinor-11beta-Prostaglandin F2alpha-d9

2,3-dinor-11beta-PGF2alpha-d9 is intended for use as an internal standard for the quantification of 2,3-dinor-11beta-PGF2alpha (Cay-16530) by GC- or LC-MS. 2,3-dinor-11beta-PGF2alpha is a metabolite of PGD2 (Cay-12010). Urinary excretion of 2,3-dinor-11beta-PGF2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-dinor-11beta-PGF2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.Formal Name: (Z)-5-((1R,2R,3S,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl-5,5,6,6,7,7,8,8,8-d9)cyclopentyl)pent-3-enoic acid. Synonyms: BPG-d9, 2,3-dinor-11beta-PGF2alpha-d9, 2,3-dinor-11-epi PGF2alpha-d9. Molecular Formula: C18H21D9O5. Formula Weight: 335.5. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CC(O)=O)[C@@H](/C=C/[C@@H](O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[C@@H](O)C1. InChi Code: InChI=1S/C18H30O5/c1-2-3-4-7-13(19)10-11-15-14(16(20)12-17(15)21)8-5-6-9-18(22)23/h5-6,10-11,13-17,19-21H,2-4,7-9,12H2,1H3,(H,22,23)/b6-5-,11-10+/t13-,14+,15+,16-,17-/m0/s1/i1D3,2D2,3D2,4D2. InChi Key: IDKLJIUIJUVJNR-RJGNUDNQSA-N.