19-alkyne Cholesterol

19-alkyne Cholesterol is an alkyne derivative of cholesterol (Cay-9003100). It has been used to track cholesterol localization and subcellular distribution in NIH3T3 cells and to study the role of cholesterol in hedgehog (Hh) signal transduction in Shh-LIGHT2 cells using click chemistry and various reporter azides.Formal Name: 10-ethynyl-19-norcholest-5-en-3beta-ol. CAS Number: 2058319-71-2. Synonyms: 19-ethynyl Cholesterol, Click TagTM 19-alkyne Cholesterol. Molecular Formula: C28H44O. Formula Weight: 396.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 0.1 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. SMILES: O[C@H](C1)CC[C@@]2(C#C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)C. InChi Code: InChI=1S/C28H44O/c1-6-28-17-14-22(29)18-21(28)10-11-23-25-13-12-24(20(4)9-7-8-19(2)3)27(25,5)16-15-26(23)28/h1,10,19-20,22-26,29H,7-9,11-18H2,2-5H3/t20-,22+,23+,24-,25+,26+,27-,28+/m1/s1. InChi Key: WJAIXDUKNKCGOR-YRPOHEEZSA-N.