17-trifluoromethylphenyl trinor Prostaglandin F2alpha methyl ester

Prostaglandin F2alpha (PGF2alpha), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2alpha is an analog of PGF2alpha that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2alpha methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2alpha. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.Formal Name: 7-[3R,5S-dihydroxy-2R-[3S-hydroxy-5Z-[3-(trifluoromethyl)phenyl]-1R-penten-1E-yl]cyclopentyl]-5-heptenoic acid, methyl ester. CAS Number: 195503-20-9. Synonyms: 17-trifluoromethylphenyl trinor PGF2alpha methyl ester. Molecular Formula: C25H33F3O5. Formula Weight: 470.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 25 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): .15 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OC)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC(C(F)(F)F)=CC=C2)[C@H](O)C1. InChi Code: InChI=1S/C25H33F3O5/c1-33-24(32)10-5-3-2-4-9-20-21(23(31)16-22(20)30)14-13-19(29)12-11-17-7-6-8-18(15-17)25(26,27)28/h2,4,6-8,13-15,19-23,29-31H,3,5,9-12,16H2,1H3/b4-2-,14-13+/t19-,20+,21+,22-,23+/m0/s1. InChi Key: SPNWWFJGYHYDNY-HCAGXNQISA-N.