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Product information "17-phenyl trinor Prostaglandin F2alpha serinol amide"
2-Arachidonyl glycerol (2-AG) exhibits cannabinoid agonist activity at the central cannabinoid (CB1) receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by COX-2 to form prostaglandin (PG) 2-glyceryl esters. These 2-glyceryl esters rapidly equilibrate to form 90:10 mixtures favoring the more stable 1-glyceryl ester. 17-phenyl trinor PGF2alpha serinol amide is a stable analog of PGF2alpha 2-glyceryl ester incorporating an activity-enhancing 17-phenyl substitution. The biological activity of 17-phenyl trinor PGF2alpha serinol amide has not yet been determined.Formal Name: N-[(2-hydroxy-1-hydroxymethyl)ethyl]-9alpha,11alpha,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide. CAS Number: 1175838-84-2. Synonyms: Bimatoprost serinol amide, 17-phenyl trinor PGF2alpha-SA. Molecular Formula: C26H39NO6. Formula Weight: 461.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH7.2): .5 mg/ml. SMILES: O[C@H](/C=C/[C@@H]1[C@@H](C/C=C\CCCC(N([H])C(CO)CO)=O)[C@@H](O)C[C@H]1O)CCC2=CC=CC=C2. InChi Code: InChI=1S/C26H39NO6/c28-17-20(18-29)27-26(33)11-7-2-1-6-10-22-23(25(32)16-24(22)31)15-14-21(30)13-12-19-8-4-3-5-9-19/h1,3-6,8-9,14-15,20-25,28-32H,2,7,10-13,16-18H2,(H,27,33)/b6-1-,15-14+/t21-,22+,23+,24-,25+/m0/s1. InChi Key: FQGNKSXLEDAGFC-LSLURRSKSA-N.
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