17-phenyl trinor Prostaglandin F2alpha methyl ester

Prostaglandin F2alpha (PGF2alpha) drives luteolysis and smooth muscle contraction by activating the FP receptor. 17-phenyl trinor PGF2alpha methyl ester is a lipophilic analog of 17-phenyl trinor PGF2alpha, a potent agonist for the FP receptor. 17-phenyl trinor PGF2alpha binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2alpha. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.Formal Name: 7-[3R,5S-dihydroxy-2R-[3S-hydroxy-5Z-phenyl-1R-penten-1E-yl]cyclopentyl]-5-heptenoic acid, methyl ester. CAS Number: 38315-47-8. Synonyms: Bimatoprost methyl ester, 17-phenyl trinor PGF2alpha methyl ester. Molecular Formula: C24H34O5. Formula Weight: 402.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Acetonitrile: 3 mg/ml, DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): .25 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OC)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1. InChi Code: InChI=1S/C24H34O5/c1-29-24(28)12-8-3-2-7-11-20-21(23(27)17-22(20)26)16-15-19(25)14-13-18-9-5-4-6-10-18/h2,4-7,9-10,15-16,19-23,25-27H,3,8,11-14,17H2,1H3/b7-2-,16-15+/t19-,20+,21+,22-,23+/m0/s1. InChi Key: UQBYFURYGYNQLQ-FDBOBMRISA-N.