17-phenyl trinor Prostaglandin F2alpha cyclopropyl methyl amide

Prostaglandin F2alpha (PGF2alpha) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2alpha binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2alpha. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2alpha ethyl amide. 17-phenyl trinor PGF2alpha ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2alpha cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2alpha. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.Formal Name: 9alpha,11alpha,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-cyclopropyl methyl amide. CAS Number: 1138395-10-4. Synonyms: 17-phenyl trinor PGF2alpha cyclopropyl methyl amide. Molecular Formula: C27H39NO4. Formula Weight: 441.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Acetonitrile: 3 mg/ml, DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): .25 mg/ml. SMILES: O[C@@H](CCC1=CC=CC=C1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(NCC3CC3)=O. InChi Code: InChI=1S/C27H39NO4/c29-22(15-14-20-8-4-3-5-9-20)16-17-24-23(25(30)18-26(24)31)10-6-1-2-7-11-27(32)28-19-21-12-13-21/h1,3-6,8-9,16-17,21-26,29-31H,2,7,10-15,18-19H2,(H,28,32)/b6-1-,17-16+/t22-,23+,24+,25-,26+/m0/s1. InChi Key: IBUQJJFOXZIFFM-SKHQJWOMSA-N.