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Product information "17-phenyl trinor Prostaglandin F2alpha 1,15-lactone"
17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) (Cay-16810) is a metabolically stable analog of PGF2alpha (Cay-16010) with potent FP receptor agonist activity and well known intraocular pressure-reducing effects. 17-phenyl trinor PF2alpha 1,15-lactone is the 1,15 lactone of 17-phenyl-trinor PGF2alpha. Selective F-series PG derivatives such as this compound have been developed for suitable pharmacologic activity and an improved side-effect profile over current glaucoma therapeutics.Formal Name: 9alpha,11alpha,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, 1,15-lactone. Synonyms: Bimatoprost free acid 1,15 lactone, 17-phenyl trinor PGF2alpha 1,15-lactone. Molecular Formula: C23H30O4. Formula Weight: 370.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 14 mg/ml, DMSO: 12.5 mg/ml, Ethanol: 16 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC2=O)[C@@H](/C=C/[C@@H](O2)CCC3=CC=CC=C3)[C@H](O)C1. InChi Code: InChI=1S/C23H30O4/c24-21-16-22(25)20-15-14-18(13-12-17-8-4-3-5-9-17)27-23(26)11-7-2-1-6-10-19(20)21/h1,3-6,8-9,14-15,18-22,24-25H,2,7,10-13,16H2/b6-1-,15-14+/t18-,19+,20+,21-,22+/m0/s1. InChi Key: RIBUBQDYGJHEOM-KDACTHKWSA-N.
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