16,16-dimethyl Prostaglandin A2

16,16-dimethyl Prostaglandin A2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10280-1 1 mg -

6 - 10 business days*

93.00€
Cay10280-5 5 mg -

6 - 10 business days*

417.00€
Cay10280-10 10 mg -

6 - 10 business days*

740.00€
 
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life.... more
Product information "16,16-dimethyl Prostaglandin A2"
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 µg/ml. Daily infusion of 10 µg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time. Formal Name: 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-5Z,10,13E-trien-1-oic acid. CAS Number: 41691-92-3. Synonyms: 16,16-dimethyl PGA2. Molecular Formula: C22H34O4. Formula Weight: 362.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: >75 mg/ml (from PGA1), DMSO: >50 mg/ml (from PGA1), Ethanol: >100 mg/ml (from PGA1), PBS pH 7.2: >2.4 mg/ml (from PGA1). lambdamax: 215 nm. SMILES: O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)C(C)(C)CCCC)C=C1. InChi Code: InChI=1S/C22H34O4/c1-4-5-16-22(2,3)20(24)15-13-17-12-14-19(23)18(17)10-8-6-7-9-11-21(25)26/h6,8,12-15,17-18,20,24H,4-5,7,9-11,16H2,1-3H3,(H,25,26)/b8-6-,15-13+/t17-,18-,20-/m1/s1. InChi Key: MOTPSJUHMGPRFZ-QEJIITRLSA-N.
Keywords: 16,16-dimethyl PGA2, 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-5Z,10,13E-trien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10280

Properties

Application: Bioactive lipid assays
MW: 362.5 D
Formula: C22H34O4
Purity: >98%
Format: Solution

Database Information

CAS : 41691-92-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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