15(R)-Iloprost

15(R)-Iloprost
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10043-500 500 µg -

3 - 10 business days*

110.00€
Cay10043-1 1 mg -

3 - 10 business days*

209.00€
Cay10043-5 5 mg -

3 - 10 business days*

880.00€
Cay10043-10 10 mg -

3 - 10 business days*

1,540.00€
 
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold... more
Product information "15(R)-Iloprost"
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP receptors with a Ki of 11 nM. 15(R)-Iloprost is the "unnatural" or inverted C-15 epimer of iloprost. This transformation frequently attenuates the biological agonist activity of prostaglandin analogs by several orders of magnitude. There are no literature reports of the biological activity of 15(R)-iloprost. Formal Name: 6,9alpha-methylene-11alpha,15R-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid. CAS Number: 85026-51-3. Molecular Formula: C22H32O4. Formula Weight: 360.5. Purity: >97%. Formulation: A solution in methyl acetate. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): .5 mg/ml. SMILES: O[C@H]1[C@H](/C=C/[C@H](O)C(C)CC#CC)[C@@H](C/C(C2)=C/CCCC(O)=O)[C@@H]2C1. InChi Code: InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15?,17-,18+,19-,20-,21+/m0/s1. InChi Key: HIFJCPQKFCZDDL-GAGQTBDJSA-N.
Keywords: 6,9alpha-methylene-11alpha,15R-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10043

Properties

Application: Bioactive lipid assays
MW: 360.5 D
Formula: C22H32O4
Purity: >97%
Format: Solution

Database Information

CAS : 85026-51-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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