15-keto-17-phenyl trinor Prostaglandin F2alpha ethyl amide

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2alpha ethyl amide (17-phenyl trinor PGF2alpha ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2alpha ethyl amide. 15-keto-17-phenyl trinor PGF2alpha ethyl amide is a potential metabolite of 17-phenyl trinor PGF2alpha ethyl amide when 17-phenyl trinor PGF2alpha ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2alpha ethyl amide have been reported.Formal Name: N-ethyl-9alpha,11alpha-dihydroxy-15-keto-17-phenyl-18,19,20-trinor-prost-5Z,13E-dien-1-amide. CAS Number: 1163135-96-3. Synonyms: 15-keto-Bimatoprost, 17-phenyl trinor PGF2alpha ethyl amide. Molecular Formula: C25H35NO4. Formula Weight: 413.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 2.5 mg/ml, DMSO: 2 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 0.5 mg/ml. lambdamax: 234 nm. SMILES: CCNC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(=O)CCc1ccccc1. InChi Code: InChI=1S/C25H35NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,21-24,28-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t21-,22-,23+,24-/m1/s1. InChi Key: OZCBJWOYRKMMPF-QWPROEHNSA-N.