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15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2, Cay-18570) is one of the... more
Product information "15-deoxy-Delta12,14-Prostaglandin J2-biotin"
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2, Cay-18570) is one of the cyclopentenone PGs, which have documented metabolic (peroxisome proliferator-activated receptor gamma-activating), antimitotic, and antiproliferative effects. The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical (i.e., non-G protein-coupled receptor) pathways. 15-deoxy-Delta12,14-PGJ2-biotin is an affinity probe which allows 15-deoxy-Delta12,14-PGJ2 to be detected through an interaction with the biotin ligand. 15-deoxy-Delta12,14-PGJ2-biotin was designed to allow 15-deoxy-Delta12,14-PGJ2 to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs.Formal Name: N-11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oyl-N'-biotinoyl-1,5-diaminopentane. Synonyms: 15-deoxy-Delta12,14-PGJ2-biotin. Molecular Formula: C35H54N4O4S. Formula Weight: 626.9. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O=C1C=C[C@H](C/C=C\CCCC(NCCCCCNC(CCCC[C@@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)/C1=C\C=C\CCCCC. InChi Code: InChI=1S/C35H54N4O4S/c1-2-3-4-5-6-11-18-28-27(22-23-30(28)40)17-10-7-8-12-20-32(41)36-24-15-9-16-25-37-33(42)21-14-13-19-31-34-29(26-44-31)38-35(43)39-34/h6-7,10-11,18,22-23,27,29,31,34H,2-5,8-9,12-17,19-21,24-26H2,1H3,(H,36,41)(H,37,42)(H2,38,39,43). InChi Key: NOEWVZWKWVGZJG-FNSZEXNBSA-N.
Keywords: | 15-deoxy-Delta12,14-PGJ2-biotin, N-11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oyl-N'-biotinoyl-1,5-diaminopentane |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10141 |
Properties
Application: | Affinity probe |
MW: | 626.9 D |
Formula: | C35H54N4O4S |
Purity: | >98% |
Format: | Solution |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H225, H302, H319, H350 |
P Phrases: | P201, P202, P210, P233, P240, P241, P242, P243, P264, P270, P280, P301+310, P303+361+353, P305+351+338, P308+313, P330, P337+313, P370+378, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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