13,14-dihydro-15-keto Prostaglandin D2

13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 (Cay-12010) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor. It also inhibits ion flux in a canine colonic mucosa preparation. In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11beta-hydroxy compounds which have also undergone beta-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine.Formal Name: 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic acid. CAS Number: 59894-07-4. Synonyms: 13,14-dihydro-15-keto PGD2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >95%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 30 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 2.5 mg/ml. SMILES: O[C@@H](C1)[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCCCC)=O)C1=O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-18,22H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+/m1/s1. InChi Key: VSRXYLYXIXYEST-KZTWKYQFSA-N.