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Product information "13,14-dehydro-15-cyclohexyl Carbaprostacyclin"
13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.Formal Name: [3aS-(2E,3aalpha,4alpha,5beta,6aalpha)]-5-[hexahydro-5-hydroxy-4-[(1-hydroxycyclohexyl)ethynyl]-2(1H)-pentalenylidene]-pentanoic acid. CAS Number: 145375-81-1. Molecular Formula: C21H30O4. Formula Weight: 346.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: >10 mg/ml, DMSO: >5 mg/ml, Ethanol: >20 mg/ml, PBS (pH 7.2): >80 mg/ml. SMILES: OC1(C#C[C@H]2[C@H](O)C[C@H]3[C@@H]2C/C(C3)=C/CCCC(O)=O)CCCCC1. InChi Code: InChI=1S/C21H30O4/c22-19-14-16-12-15(6-2-3-7-20(23)24)13-18(16)17(19)8-11-21(25)9-4-1-5-10-21/h6,16-19,22,25H,1-5,7,9-10,12-14H2,(H,23,24)/b15-6+/t16-,17+,18-,19+/m0/s1. InChi Key: LGIPMFCHTFFLFR-PRYZLTTQSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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