11(Z),14(Z)-Eicosadienoic Acid methyl ester

11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the omega-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid (Cay-90330), a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5'-monophosphate dehydrogenase (Ki = 3.1 µM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki = 3.0 µM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance. Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.Formal Name: 11Z,14Z-eicosadienoic acid, methyl ester. CAS Number: 61012-46-2. Synonyms: SFE 21:2. Molecular Formula: C21H38O2. Formula Weight: 322.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 0.5 mg/ml. lambdamax: 267, 280, 362 nm. SMILES: CCCCC/C=C\C/C=C\CCCCCCCCCC(OC)=O. InChi Code: InChI=1S/C21H38O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(22)23-2/h7-8,10-11H,3-6,9,12-20H2,1-2H3/b8-7-,11-10-. InChi Key: GWJCFAOQCNNFAM-NQLNTKRDSA-N.