(±)11(12)-EET methyl ester

(±)11(12)-EET (Cay-50511) is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)11(12)-EET has been shown, along with (±)8(9)-EET (Cay-50351), to play a role in the recovery of depleted Ca2+ pools in cultured smooth muscle cells. (±)11(12)-EET methyl ester is a more stable for used for long-term storage. It can be readily hydrolyzed to the free acid as needed.Formal Name: (±)11,12-epoxy-5Z,8Z,14Z-eicosatrienoic acid, methyl ester. Synonyms: (±)11,12-EpETrE methyl ester. Molecular Formula: C21H34O3. Formula Weight: 334.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. SMILES: CCCCC/C=C\C[C@@H]1[C@@H](O1)C/C=C\C/C=C\CCCC(OC)=O. InChi Code: InChI=1S/C21H34O3/c1-3-4-5-6-10-13-16-19-20(24-19)17-14-11-8-7-9-12-15-18-21(22)23-2/h7,9-11,13-14,19-20H,3-6,8,12,15-18H2,1-2H3/b9-7-,13-10-,14-11-/t19-,20+/m1/s1. InChi Key: DHUPCTVGLDZJCY-AFRPMPIESA-N.