Detergents

Detergents are amphiphilic, organic chemicals. These substances, also called surfactants (surface active agents), possess a lipophilic tail and a hydrophilic head group. Detergents like Triton X-100 form stable interphases between hydrophobic and hydrophilic compounds. This results in the solubilization of the hydrophobic molecules in water. In research, detergents are used for cell lysis, isolation of poorly soluble proteins (e.g. transmembrane receptors) and for membrane permeabilization. Here, you will find a wide array of non-ionic, cationic, anionic and zwitterionic detergents.

Detergents are amphiphilic, organic chemicals. These substances, also called surfactants ( surf ace act ive a ge nts ), possess a lipophilic tail and a hydrophilic head group. Detergents like... read more »
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Detergents

Detergents are amphiphilic, organic chemicals. These substances, also called surfactants (surface active agents), possess a lipophilic tail and a hydrophilic head group. Detergents like Triton X-100 form stable interphases between hydrophobic and hydrophilic compounds. This results in the solubilization of the hydrophobic molecules in water. In research, detergents are used for cell lysis, isolation of poorly soluble proteins (e.g. transmembrane receptors) and for membrane permeabilization. Here, you will find a wide array of non-ionic, cationic, anionic and zwitterionic detergents.

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CHAPSO ((3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate))
CHAPSO...

Item number: C3500.25

Non-denaturing zwitterionic detergent with cholic acid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection. Designed by Good, et al., and typically referred...
CAS 82473-24-3
MW: 630.90 D
From 679.00€ *
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n-Octyl-beta-D-thioglucopyranoside
n-Octyl-beta-D-thioglucopyranoside

Item number: Cay17184-1

n-Octyl-beta-D-thioglucopyranoside (OTG) is a low molecular weight nonionic detergent that is commonly used for cell lysis and non-denaturing protein solubilization. It has a critical micelle concentration of 7.9-9.0 mM. OTG is stable in aqueous solutions, resistant to degradation by beta-glucosidases, and easily...
Keywords: Octylthioglucoside, OTG, octyl 1-thio-beta-D-glucopyranoside
Application: Cell lysis, Non-denaturing protein solubilization
CAS 85618-21-9
MW: 308.4 D
From 43.00€ *
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n-Octyl-beta-D-thioglucopyranoside (ultrapure)
n-Octyl-beta-D-thioglucopyranoside (ultrapure)

Item number: AG-CC1-0005-G001

Soluble in water or methanol. ? 99% (HPLC) [alpha-Isomer <0.01% (HPLC)] [n-Octanthiol <0.001% (HPLC)] Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. The thioether linkage makes it resistant to degradation by beta-glucosidase enzymes. For the stabilization...
Keywords: OTG, Octylthioglucoside, n-Octyl 1-thio-beta-D-glucopyranoside
Application: Non-ionic detergent, Crystallography
CAS 85618-21-9
MW: 308,4 D
From 61.00€ *
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FLAC6
FLAC6

Item number: Cay24781-100

FLAC6 is a detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 0.56 mM.Formal Name:...
Keywords: (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-N-(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononyl)-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-...
Application: Membrane protein solubilization
CAS 2820046-26-0
MW: 717.4 D
From 285.00€ *
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FTAC8
FTAC8

Item number: Cay24787-250

FTAC8 is a detergent that can be used to stabilize membrane proteins. It has a critical micelle concentration (CMC) of 0.02 mM. It has been used in the cell-free synthesis and purification of histidine-tagged MscL, a mechanosensitive membrane channel, as well as in the insertion of MscL into liposomes. FTAC8 has...
Keywords: C8F-TAC,...
Application: Membrane protein stabilization
324.00€ *
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FTAC6
FTAC6

Item number: Cay24786-250

FTAC6 is a detergent that can be used to stabilize membrane proteins. It has a critical micelle concentration (CMC) of 0.37 mM. It has been used in the cell-free synthesis and purification of histidine-tagged MscL, a mechanosensitive membrane channel, as well as in the insertion of MscL into liposomes. FTAC6 has...
Keywords: N1,N3,N5,N7,N9,N11-hexakis(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-12-((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)t...
Application: Membrane protein stabilization
From 352.00€ *
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DLAC
DLAC

Item number: Cay24780-250

DLAC is a detergent synthesized from lactobionic acid. It can be used to solubilize membrane proteins and has a critical micelle concentration (CMC) of 1.3 mM.Formal Name: N-decyl-4-O-beta-D-galactopyranosyl-D-gluconamide. CAS Number: 70803-56-4. Molecular Formula: C22H43NO11. Formula Weight: 497.6. Purity: >97%....
Keywords: N-decyl-4-O-beta-D-galactopyranosyl-D-gluconamide
Application: Membrane protein solubilization
CAS 70803-56-4
MW: 497.6 D
448.00€ *
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ODG
ODG

Item number: Cay24782-100

ODG is a detergent used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of greater than 10 mM.Formal Name: N-(2-methyl-1,3-bis((3R,4S,5S-trihydroxy-6R-(hydroxymethyl)tetrahydro-2H-pyran-2R-yl)oxy)propan-2-yl)-3-(octylthio)propanamide. CAS Number: 2350271-85-9. Molecular Formula:...
Keywords: N-(2-methyl-1,3-bis((3R,4S,5S-trihydroxy-6R-(hydroxymethyl)tetrahydro-2H-pyran-2R-yl)oxy)propan-2-yl)-3-(octylthio)propana...
Application: Membrane protein solubilization
CAS 2350271-85-9
MW: 629.8 D
From 422.00€ *
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CALXGLUK
CALXGLUK

Item number: Cay24784-10

CALXGLUK is a calixarene detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 0.025 mM. CALXGLUK has been used to solubilize a membrane GPCR (MP-A) and a membrane transporter (MP-B) from yeast alone and in combination with Triton X-100 (Cay-600217) and...
Keywords: (2R,2'R,2''R,3S,3'S,3''S,4S,4'S,4''S,5R,5'R,5''R,6R,6'R,6''R)-6,6',6''-(((((72-(heptyloxy)-12,32,52-trimethoxy-1,3,5,7(1,3...
Application: Membrane protein solubilization
CAS 1820596-85-7
MW: 1426.6 D
From 411.00€ *
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MEGA-10
MEGA-10

Item number: Cay25703-1

MEGA-10 is a nonionic detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 4.88 mM under no salt conditions, which decreases in the presence of sodium chloride. MEGA-10 has been used to reconstitute amino acid transporters from rat liver plasma membrane...
Keywords: N-decanoyl-N-Methylglucamine, 1-deoxy-1-[methyl(1-oxodecyl)amino]-D-glucitol
Application: Nonionic detergent
CAS 85261-20-7
MW: 349.5 D
From 65.00€ *
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MEGA-8
MEGA-8

Item number: Cay25701-1

MEGA-8 is a nonionic detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 70 mM under no-salt conditions and CMCs ranging from 5 to 64 mM under high and low salt conditions for a variety of salts.Formal Name: 1-deoxy-1-[methyl(1-oxooctyl)amino]-D-glucitol. CAS...
Keywords: N-octanoyl-N-Methylglucamine, 1-deoxy-1-[methyl(1-oxooctyl)amino]-D-glucitol
Application: Nonionic detergent
CAS 85316-98-9
MW: 321.4 D
From 100.00€ *
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MEGA-9
MEGA-9

Item number: Cay25702-1

MEGA-9 is a nonionic detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 20 mM under no-salt conditions and CMCs ranging from 2 to 17.1 mM under high and low salt conditions for a variety of salts. It has been used to solubilize the melibiose transport carrier...
Keywords: Nonanoyl-N-Methylglucamide, 1-deoxy-1-[methyl(1-oxononyl)amino]-D-glucitol
Application: Nonionic detergent
CAS 85261-19-4
MW: 335.4 D
From 60.00€ *
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