Vincamine

Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain. Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 µM and has been explored as a pharmacotherapy to treat cerebral metabolic and vascular diseases.Formal Name: (3alpha,14beta,16alpha)-14,15-dihydro-14-hydroxy-eburnamenine-14-carboxylic acid, methyl ester. CAS Number: 1617-90-9. Synonyms: Angiopac, Devincan, Equipur, Minorin, NSC 91998, Novicet, Oxybral, Perval, Sostenil, Tripervan. Molecular Formula: C21H26N2O3. Formula Weight: 354.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.25 mg/ml. lambdamax: 227, 281 nm. SMILES: CC[C@]1(CCC2)C[C@@](C(OC)=O)(O)N3C4=CC=CC=C4C5=C3[C@@]1([H])N2CC5. InChi Code: InChI=1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1. InChi Key: RXPRRQLKFXBCSJ-GIVPXCGWSA-N. Origin: Plant/Vinca minor, Plant/Catharanthus roseus.