Valganciclovir (hydrochloride)

Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Cay-13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection. Formulations containing valganciclovir have been used in the prevention of post-transplant cytomegalovirus (CMV) infections.Formal Name: 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-valine, monohydrochloride. CAS Number: 175865-59-5. Synonyms: Ro 107-9070/194. Molecular Formula: C14H22N6O5 . HCl. Formula Weight: 390.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 255 nm. SMILES: CC(C)[C@H](N)C(OCC(CO)OCN1C(NC(N)=NC2=O)=C2N=C1)=O.Cl. InChi Code: InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22,/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22),1H/t8?,9-,/m0./s1. InChi Key: ZORWARFPXPVJLW-MTFPJWTKSA-N.