Valganciclovir-d5 (hydrochloride)

Valganciclovir-d5 is intended for use as an internal standard for the quantification of valganciclovir (Cay-13875) by GC- or LC-MS. Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Cay-13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection. Formulations containing valganciclovir have been used in the prevention of post-transplant cytomegalovirus (CMV) infections.Formal Name: DL-valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl-1,1,2,3,3-d5 ester, monohydrochloride. Molecular Formula: C14H17D5N6O5 . HCl. Formula Weight: 395.9. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble, Water: soluble. SMILES: CC(C)C(N)C(OC([2H])([2H])C(C([2H])([2H])O)([2H])OCN1C(NC(N)=NC2=O)=C2N=C1)=O.Cl. InChi Code: InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22,/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22),1H/i3D2,4D2,8D,. InChi Key: ZORWARFPXPVJLW-KZUFOJGHSA-N.