Troxipide

Troxipide is an antiulcerative agent. It inhibits production of superoxide induced by N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP, Cay-21495) in, and IL-8-induced migration of, isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 1 mM. Troxipide (100 and 200 mg/kg, i.p.) reduces the lesion size of gastric ulcers induced by diclofenac (Cay-70680, Cay-22983) in rats.Formal Name: 3,4,5-trimethoxy-N-3-piperidinyl-benzamide. CAS Number: 30751-05-4. Synonyms: KU-54. Molecular Formula: C15H22N2O4. Formula Weight: 294.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 3mg/mL, DMF:PBS (pH 7.2) (1:5): 0.16mg/mL, Ethanol: 2mg/mL. lambdamax: 216, 262 nm. SMILES: O=C(C1=CC(OC)=C(OC)C(OC)=C1)NC2CCCNC2. InChi Code: InChI=1S/C15H22N2O4/c1-19-12-7-10(8-13(20-2)14(12)21-3)15(18)17-11-5-4-6-16-9-11/h7-8,11,16H,4-6,9H2,1-3H3,(H,17,18). InChi Key: YSIITVVESCNIPR-UHFFFAOYSA-N.