trans-Zeatin

trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities. It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM. trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner. It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 µM. trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid beta (25-35) (Abeta25-35) in PC12 cells. It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.Formal Name: 2E-methyl-4-(9H-purin-6-ylamino)-2-buten-1-ol. CAS Number: 1637-39-4. Molecular Formula: C10H13N5O. Formula Weight: 219.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/ml, DMSO: 3 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml. lambdamax: 210, 269 nm. SMILES: OC/C(C)=C/CNC1=NC=NC2=C1N=CN2. InChi Code: InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+. InChi Key: UZKQTCBAMSWPJD-FARCUNLSSA-N.