trans-trismethoxy Resveratrol

trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 µM, respectively). trans-trismethoxy Resveratrol (15 µM) inhibits TNF-alpha-induced activation of NF-kappaB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 µM.Formal Name: 1,3-dimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene. CAS Number: 22255-22-7. Synonyms: (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzene diol, TMS, trans-3,5,4'-trimethoxystilbene. Molecular Formula: C17H18O3. Formula Weight: 270.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 10 mg/ml. lambdamax: 218, 306, 319 nm. SMILES: COc1ccc(cc1)\C=C/c1cc(OC)cc(OC)c1. InChi Code: InChI=1S/C17H18O3/c1-18-15-8-6-13(7-9-15)4-5-14-10-16(19-2)12-17(11-14)20-3/h4-12H,1-3H3/b5-4+. InChi Key: GDHNBPHYVRHYCC-SNAWJCMRSA-N.