trans-11-Methyl-2-dodecenoic acid

Off-white crystalline powder. Soluble in ethanol (30mg/ml), DMSO or DMF. Chemical. CAS: 677354-24-4. Formula: C13H24O2. MW: 212.3. Synthetic. trans-Delta2-11-methyl-Dodecenoic acid is the conformational isomer of cis-Delta2-11-methyl-dodecenoic acid, a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems. Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. In a DSF bioassay, the minimum concentration of cis-Delta2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of trans-Delta2-11-methyl-dodecenoic acid and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).