SOTS-1 (technical grade)

Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature. This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo.Formal Name: 4,4'-[azobis(oxymethylene]bis-benzoic acid. CAS Number: 223507-96-8. Synonyms: Superoxide Thermal Source, Di-(4-Carboxybenzyl)Hyponitrite. Molecular Formula: C16H14N2O6. Formula Weight: 330.3. Purity: >80%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMF:PBS(pH 7.2)(1:2): 0.3 mg/ml, DMSO: 10 mg/ml. SMILES: O=C(O)C1=CC=C(CON=NOCC2=CC=C(C(O)=O)C=C2)C=C1. InChi Code: InChI=1S/C16H14N2O6/c19-15(20)13-5-1-11(2-6-13)9-23-17-18-24-10-12-3-7-14(8-4-12)16(21)22/h1-8H,9-10H2,(H,19,20)(H,21,22). InChi Key: KNKCXZHPOIMNJH-UHFFFAOYSA-N.