SLF1081851 (hydrochloride)

SLF1081851 is an inhibitor of sphingosine-1-phosphate (S1P) transporter (SPNS2). It inhibits mouse Spns2 by 67% when used at a concentration of 2 µM. SLF1081851 inhibits S1P export from HeLa cells expressing mouse Spns2 (IC50 = 1.93 µM). In vivo, SLF1081851 (20 mg/kg) decreases blood lymphocyte numbers and plasma S1P levels in mice.Formal Name: 3-(4-decylphenyl)-1,2,4-oxadiazole-5-propanamine, hydrochloride. Molecular Formula: C21H33N3O . HCl. Formula Weight: 380.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly soluble, Water: Slightly soluble. SMILES: NCCCC1=NC(C2=CC=C(CCCCCCCCCC)C=C2)=NO1.Cl. InChi Code: InChI=1S/C21H33N3O.ClH/c1-2-3-4-5-6-7-8-9-11-18-13-15-19(16-14-18)21-23-20(25-24-21)12-10-17-22,/h13-16H,2-12,17,22H2,1H3,1H. InChi Key: ZJJXKBLUUGLWDW-UHFFFAOYSA-N.