S-Adenosylhomocysteine

S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative and an intermediate, by-product, or modulator of several metabolic pathways, including the activated methyl cycle and cysteine biosynthesis. It is also a product of S-adenosyl-methionine (SAM)-dependent methylation of biological molecules, including DNA, RNA, and histones and other proteins. SAH is a risk factor for many diseases, including cancer and neurodegenerative diseases. In addition, inhibitors that block its hydrolysis are being developed as anti-viral, anti-parasitic, anti-arthritic and immunosuppressive agents.Formal Name: S-(5'-deoxyadenosin-5'-yl)-L-homocysteine. CAS Number: 979-92-0. Synonyms: AdoHcy, SAH. Molecular Formula: C14H20N6O5S. Formula Weight: 384.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: 1M HCl: 20 mg/ml. lambdamax: 260 nm. SMILES: O[C@@H]1[C@H](O)[C@@H](CSCC[C@H](N)C(O)=O)O[C@H]1N2C(N=CN=C3N)=C3N=C2. InChi Code: InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6?,7-,9-,10-,13-/m1/s1. InChi Key: ZJUKTBDSGOFHSH-ZRURSIFKSA-N.