(±)-Norepinephrine-d6 (hydrochloride)

(±)-Norepinephrine-d6 is intended for use as an internal standard for the quantification of norepinephrine (Cay-35580) by GC- or LC-MS. (±)-Norepinephrine is a racemic mixture of the endogenous neurotransmitter (-)-norepinephrine (Cay-16673) and (+)-norepinephrine. It induces cAMP accumulation in rat cerebral cortical membranes when used at concentrations ranging from 1 to 100 µM. (±)-Norepinephrine induces contraction of bovine anterior cerebral, middle cerebral, and internal carotid arterial strips (EC50s = 0.91, 0.92, and 0.87 µM, respectively) but induces relaxation of bovine posterior cerebral arterial strips (EC50 = 0.95 µM). Formulations containing (±)-norepinephrine have been used for the restoration of blood pressure in acute hypotensive states.Formal Name: 4-(2-amino-1-hydroxyethyl-1,2,2-d3)-1,2-benzene-3,4,6-d3-diol, monohydrochloride. CAS Number: 1219803-04-9. Synonyms: (±)-Arterenol-d6, DL-Noradrenaline-d6, (±)-Noradrenaline-d6, DL-Norepinephrine-d6. Molecular Formula: C8H5D6NO3 . HCl. Formula Weight: 211.7. Purity: >99% (deuterated forms d1-d6). Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble, Water: Slightly soluble. SMILES: OC1=C(O)C([2H])=C(C([2H])(O)C([2H])([2H])N)C([2H])=C1[2H].Cl. InChi Code: InChI=1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5,/h1-3,8,10-12H,4,9H2,1H/i1D,2D,3D,4D2,8D,. InChi Key: FQTFHMSZCSUVEU-GVFLBQLQSA-N.