Nanangenine F

Nanangenine F is a drimane sesquiterpene fungal metabolite that has been found in A. nanangensis. It is active against B. subtilis (IC50 = 78 µg/ml) and cytotoxic to NS-1, DU145, and MCF-7 cancer and NFF non-cancerous cells (IC50s = 49, 95, 49, and 84 µg/ml, respectively).Formal Name: (1R,4R,4aR,5R,8aS)-4-formyl-4,5-dihydroxy-3,4a,8,8-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl hexanoate. Molecular Formula: C21H34O5. Formula Weight: 366.5. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: CC1(C)CC[C@@H](O)[C@@]2(C)[C@@]1([H])[C@H](OC(CCCCC)=O)C=C(C)[C@]2(O)C=O. InChi Code: InChI=1S/C21H34O5/c1-6-7-8-9-17(24)26-15-12-14(2)21(25,13-22)20(5)16(23)10-11-19(3,4)18(15)20/h12-13,15-16,18,23,25H,6-11H2,1-5H3/t15-,16-,18+,20+,21-/m1/s1. InChi Key: YBVXMQREWROXKL-XDISJUHXSA-N. Origin: Fungus/Aspergillus nanangensis.