N-4-Tosyl-L-arginine methyl ester (hydrochloride)

N-4-Tosyl-L-arginine methyl ester (TAME) is a synthetic substrate of serine proteases, including thrombin, trypsin, chymotrypsin, and kallikreins. It can be used to evaluate serine proteases from diverse sources. TAME also binds to and inhibits anaphase-promoting complex, a ubiquitin ligase, in Xenopus egg extract.Formal Name: N2-[(4-methylphenyl)sulfonyl]-L-arginine, methyl ester, monohydrochloride. CAS Number: 1784-03-8. Synonyms: TAME, Tosylarginine methyl ester. Molecular Formula: C14H22N4O4S . HCl. Formula Weight: 378.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 228 nm. SMILES: CC1=CC=C(S(N[C@H](C(OC)=O)CCCNC(N)=N)(=O)=O)C=C1.Cl. InChi Code: InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16,/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17),1H/t12-,/m0./s1. InChi Key: JIQFFACVQXXHMY-YDALLXLXSA-N.