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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay28193-1 | 1 mg | - |
6 - 10 business days* |
481.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Myrothecine A is a trichothecene mycotoxin that has been found in M. roridum and has anticancer... more
Product information "Myrothecine A"
Myrothecine A is a trichothecene mycotoxin that has been found in M. roridum and has anticancer activities. It inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells (IC50s = 95, 70, 60, and 25 µM, respectively). Myrothecine A (50 µM) induces G1 cell cycle arrest in HepG2 cells, as well as increases Bax and cleaved caspase-3, -5, and -8 levels and induces apoptosis in SMMC-7721 cells.Formal Name: (2R,4R,7Z,11S,15E,19aR,22S,23S,23aR,25R,26S,27R)-11-acetyl-3,4,10,11,21,22,23,23a-octahydro-22,25,27-trihydroxy-22,26-dimethyl-20H-11,15-methano-23,2,4,19a-[1,2]propanediyl[3]ylidene-2H,13H,19H-1,5,12,18-benzotetraoxacycloheneicosin-6,17(9H,14H)-dione. CAS Number: 910292-40-9. Molecular Formula: C29H38O10. Formula Weight: 546.6. Purity: >70%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: O[C@]1(C)CC[C@@]2(COC(/C=C3[C@@H](O)[C@@]4(C(C)=O)OCC\3)=O)[C@@]5([H])[C@]1([H])C[C@@]6(O)[C@]2(C)[C@@](OC(/C=C/CC4)=O)([H])C[C@@]6([H])O5. InChi Code: InChI=1S/C29H38O10/c1-16(30)28-8-5-4-6-21(31)38-19-13-20-29(35)14-18-24(39-20)27(26(19,29)3,10-9-25(18,2)34)15-36-22(32)12-17(23(28)33)7-11-37-28/h4,6,12,18-20,23-24,33-35H,5,7-11,13-15H2,1-3H3/b6-4+,17-12-/t18-,19+,20+,23+,24+,25+,26+,27+,28+,29-/m0/s1. InChi Key: HGVKMRAJPCHSPC-MAJSWSFESA-N.
Keywords: | (2R,4R,7Z,11S,15E,19aR,22S,23S,23aR,25R,26S,27R)-11-acetyl-3,4,10,11,21,22,23,23a-octahydro-22,25,27-trihydroxy-22,26-dimethyl-20H-11,15-methano-23,2,4,19a-[1,2]propanediyl[3]ylidene-2H,13H,19H-1,5,12,18-benzotetraoxacycloheneicosin-6,17(9H,14H)-dione |
Supplier: | Cayman Chemical |
Supplier-Nr: | 28193 |
Properties
Application: | Antineoplastic mycotoxin |
MW: | 546.6 D |
Formula: | C29H38O10 |
Purity: | >70% |
Format: | Solid |
Database Information
CAS : | 910292-40-9| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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