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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-27708 | 1 mg | - | - |
3 - 15 business days* |
644.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Containing the active ingredient of MLN4924 which acts as a substrate-assisted inhibitor of the... more
Product information "MLN-4924"
Containing the active ingredient of MLN4924 which acts as a substrate-assisted inhibitor of the NEDD8-activating enzyme (NAE). NAE activates NEDD8 (Neural precursor cell expressed, developmentally down-regulated 8) for conjugation to a variety of ubiquitin E3 ligases. NAE inhibitor binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. This cell permeable compound selectively inhibits NAE activity and results in inhibition of the NEDD8 pathway. Treatment of cells with MLN4924 results in inhibition of the NEDD8 pathway, making MLN4924 a new approach to targeting the UPS for the treatment of cancer.
Keywords: | NEDD8-activating enzyme inhibitor, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 27708 |
Properties
Application: | NEDD activating enzyme ?(NAE)? inhibitor |
MW: | 443.2 D |
Formula: | C21H25N5O4S |
Database Information
KEGG ID : | K10686 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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