ML-192

ML-192 is an antagonist of GPR55 (IC50 = 702 nM). It is selective for GPR55 over the cannabinoid (CB) receptors CB1 and CB2, as well as GPR35 (IC50s = >32 µM).Formal Name: 2-furanyl[4-(5,6,7,8-tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-methanone. CAS Number: 460331-61-7. Synonyms: CID-1434953. Molecular Formula: C20H22N4O2S. Formula Weight: 382.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 5 mg/ml, Ethanol: 15 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.30 mg/ml. lambdamax: 235, 292 nm. SMILES: O=C(C1=CC=CO1)N2CCN(C3=C4C(SC5=C4CCCC5)=NC(C)=N3)CC2. InChi Code: InChI=1S/C20H22N4O2S/c1-13-21-18(17-14-5-2-3-7-16(14)27-19(17)22-13)23-8-10-24(11-9-23)20(25)15-6-4-12-26-15/h4,6,12H,2-3,5,7-11H2,1H3. InChi Key: GDPDARVUXXOYAJ-UHFFFAOYSA-N.