MDL 12330A (hydrochloride)

MDL 12330A is an adenylyl cyclase inhibitor that can also inhibit cAMP and cGMP phosphodiesterases and block slow extracellular and store-operated Ca2+ entry into cells. It is widely used to investigate the role of the adenylyl cyclase/cAMP signaling pathway. MDL 12330A has also been reported to block voltage-dependent K+ channels, extend action potential duration, and enhance insulin secretion in pancreatic beta-cells.Formal Name: rel-N-[(1R,2R)-2-phenylcyclopentyl]-azacyclotridec-1-en-2-amine, monohydrochloride. CAS Number: 40297-09-4. Synonyms: RMI 12330A. Molecular Formula: C23H36N2 . HCl. Formula Weight: 377.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, Ethanol: 1 mg/ml. lambdamax: 210 nm. SMILES: C1(/N[C@@H]2[C@H](C3=CC=CC=C3)CCC2)=N\CCCCCCCCCCC1.Cl. InChi Code: InChI=1S/C23H36N2.ClH/c1-2-4-6-11-18-23(24-19-12-7-5-3-1)25-22-17-13-16-21(22)20-14-9-8-10-15-20,/h8-10,14-15,21-22H,1-7,11-13,16-19H2,(H,24,25),1H/t21-,22-,/m0./s1. InChi Key: CKOPQUCSDBVAQG-VROPFNGYSA-N.