MCI-186

MCI-186 is a free radical scavenger with diverse protective effects in vivo. Most notably, it reduces damage due to ischemia-reperfusion injury in lung, liver, and brain in animal models of transplant, infection, traumatic brain injury, and stroke. MCI-186 provides these protective effects, at least in part, by reducing reactive oxygen species, inhibiting apoptosis, and blocking nonenzymatic peroxidation and lipoxygenase activity.Formal Name: 2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one. CAS Number: 89-25-8. Synonyms: Edaravone, NSC 2629. Molecular Formula: C10H10N2O. Formula Weight: 174.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 30 mg/ml, Ethanol: 15 mg/ml. lambdamax: 244 nm. SMILES: O=C(CC(C)=N1)N1C2=CC=CC=C2. InChi Code: InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3. InChi Key: QELUYTUMUWHWMC-UHFFFAOYSA-N. Origin: Synthetic.