Lythrine

Lythrine is an alkaloid originally isolated from H. salicifolia that inhibits prostaglandin synthetase (IC50 = 469 µM).Formal Name: (4aS,6S,9Z,20S)-2,3,4,4a,5,6-hexahydro-14-hydroxy-17,18-20H-6,20-methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one. CAS Number: 5286-10-2. Synonyms: (+)-Lythrine. Molecular Formula: C26H29NO5. Formula Weight: 435.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 1 mg/ml. lambdamax: 284 nm. SMILES: COC1=CC([C@@]2([H])N3CCCC[C@@]3([H])C[C@@]4([H])C2)=C(C5=CC(/C=C\C(O4)=O)=CC=C5O)C=C1OC. InChi Code: InChI=1S/C26H29NO5/c1-30-24-14-19-20(15-25(24)31-2)22-13-18(12-17-5-3-4-10-27(17)22)32-26(29)9-7-16-6-8-23(28)21(19)11-16/h6-9,11,14-15,17-18,22,28H,3-5,10,12-13H2,1-2H3/b9-7-/t17-,18-,22-/m0/s1. InChi Key: WCZWUYYJZVBKDZ-ZQMQQCDVSA-N. Origin: Plant/Heimia salicifolia.