LipidLaunch(TM) LP-01 LNP (Luciferase)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39896-5 5 µg -

6 - 10 business days*

479.00€
 
LipidLaunch(TM) LP-01 LNP (Luciferase) is a solution containing lipid nanoparticles (LNPs)... more
Product information "LipidLaunch(TM) LP-01 LNP (Luciferase)"
LipidLaunch(TM) LP-01 LNP (Luciferase) is a solution containing lipid nanoparticles (LNPs) composed of the ionizable cationic amino lipid LP-01 (Cay-37278), cholesterol (Cay-9003100, Cay-39088), the phospholipid 1,2-distearoyl-sn-glycero-3-PC (Cay-15100, Cay-39189), and the lipid excipient DMG-PEG(2000) (Cay-33945) at a molar ratio of 45:44:9:2 and encapsulating mRNA encoding firefly luciferase protein. It is intended for proof-of-concept experiments to determine whether LP-01-based LNPs can effectively lead to the expression of a protein of interest in a target cell type, either in vitro or in vivo. Firefly luciferase is an enzyme that catalyzes the oxidation of ATP-dependent D-luciferin, resulting in chemiluminescence at a wavelength of approximately 560 nm. Suggested in vitro use: Thaw LNPs on ice with occasional gentle swirling (do not vortex). Using a gentle pipetting technique, dilute 1:100-1:500 in complete cell culture media (with serum) and add to subconfluent cells in a luminescence-compatible tissue culture plate. Use a luciferase reporter assay substrate and read luminescence on a plate reader. Optimal conditions are highly dependent on cell type.Synonyms: LipidLaunch(TM) CIN-16645 LNP (Luciferase). Formulation: (Request formulation change), TBS, pH 7.5, with 10% sucrose.
Keywords: LipidLaunch(TM) CIN-16645 LNP (Luciferase), Luciferin 4-monooxygenase
Supplier: Cayman Chemical
Supplier-Nr: 39896

Properties

Application: LP-01-based LNP solution for expressing luciferase
Format: Solution

Database Information

UniProt ID : P08659 | Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H402
P Phrases: P264, P273, P280, P302+352, P305+351+338, P321, P332+313, P337+313, P362+364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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