Lecanoric Acid

Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens. It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 µg/ml for lecanoric and ascorbic acid, respectively). Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 µg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties.Formal Name: 2,4-dihydroxy-6-methyl-benzoic acid, 4-carboxy-3-hydroxy-5-methylphenyl ester. CAS Number: 480-56-8. Synonyms: NSC 249981. Molecular Formula: C16H14O7. Formula Weight: 318.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: CC1=CC(OC(C2=C(C)C=C(O)C=C2O)=O)=CC(O)=C1C(O)=O. InChi Code: InChI=1S/C16H14O7/c1-7-3-9(17)5-11(18)14(7)16(22)23-10-4-8(2)13(15(20)21)12(19)6-10/h3-6,17-19H,1-2H3,(H,20,21). InChi Key: HEMSJKZDHNSSEW-UHFFFAOYSA-N. Origin: Fungus/Parmotrema sp..