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L-Serine is a non-essential amino acid. It is produced from 3-phosphoglycerate in a multistep biosynthesis catalyzed by phosphoglycerate dehydrogenase (PGDH), phosphoserine aminotransferase (PSAT), and phosphoserine phosphatase (PSP). L-Serine can also be derived from dietary sources, as well as protein and phospholipid turnover. Defective L-serine biosynthesis is associated with neural tube defects and deoxysphingolipid accumulation in patients with Neu-Laxova syndrome, a rare disease characterized by a mutation in PGDH. Dysregulation of L-serine phosphorylation is associated with disease progression in patients with neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis.CAS Number: 56-45-1. Synonyms: (S)-Serine. Molecular Formula: C3H7NO3. Formula Weight: 105.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble. SMILES: OC([C@@H](N)CO)=O. InChi Code: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1. InChi Key: MTCFGRXMJLQNBG-REOHCLBHSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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