KY 02111

KY 02111 promotes the differentiation of human pluripotent stem cells to cardiomyocytes by inhibiting Wnt signaling. Treatment with 10 µM of KY 02111 has been shown to increase the ratio of beating cardiac colonies by 70-94% in cell aggregates of the embryonic stem cell lines KhES-1 and KhES-3 as well as the induced pluripotent stem cell lines 253G1, IMR90-1, IMR90-4, and RCHIPC0003.Formal Name: N-(6-chloro-2-benzothiazolyl)-3,4-dimethoxy-benzenepropanamide. CAS Number: 1118807-13-8. Molecular Formula: C18H17ClN2O3S. Formula Weight: 376.9. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 10 mg/ml. lambdamax: 204, 223, 281, 304 nm. SMILES: ClC1=CC=C2C(SC(NC(CCC3=CC=C(OC)C(OC)=C3)=O)=N2)=C1. InChi Code: InChI=1S/C18H17ClN2O3S/c1-23-14-7-3-11(9-15(14)24-2)4-8-17(22)21-18-20-13-6-5-12(19)10-16(13)25-18/h3,5-7,9-10H,4,8H2,1-2H3,(H,20,21,22). InChi Key: LXFKEVQQSKQXPR-UHFFFAOYSA-N.