Kibdelone B

Kibdelones are natural aromatic polyketides first isolated from an actinomycete, Kibdelosporangium. They exhibit potent and selective cytotoxicity against a panel of human tumor cell lines. Kibdelones also display significant antibacterial and nematocidal activity. Kibdelone B is a member of this group that undergoes facile equilibration to kibdelones A-C under mild conditions. Its mode of action and pharmacology have not been studied.Formal Name: (10R,12R,13S)-rel-(+)-4-chloro-6,7,10,11,12,13-hexahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. CAS Number: 934464-78-5. Molecular Formula: C29H26ClNO10. Formula Weight: 584.0. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: O=C1N(C)C(CCC)=C(Cl)C2=C1C(C3=C(C2=O)CCC(C3=C4O)=C(OC)C5=C4C(C6=C(O5)[C@@H](O)C[C@H](O)[C@@H]6O)=O)=O. InChi Code: InChI=1S/C29H26ClNO10/c1-4-5-11-20(30)16-17(29(39)31(11)2)23(36)14-9(21(16)34)6-7-10-15(14)24(37)19-25(38)18-22(35)12(32)8-13(33)27(18)41-28(19)26(10)40-3/h12-13,22,32-33,35,37H,4-8H2,1-3H3/t12-,13-,22-/m0/s1. InChi Key: NLEKAAIWXVERFW-MZFXBISCSA-N. Origin: Bacterium/Kibdelosporangium sp..