Isocurcumenol

Isocurcumenol is a sesquiterpene that has been found in C. zedoaria rhizomes and has diverse biological activities. Isocurcumenol inhibits LPS-induced production of nitric oxide (NO) in isolated mouse peritoneal macrophages. It reduces LPS/D-galactosamine-induced increases in serum levels of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) in a mouse model of liver injury when administered at a dose of 50 mg/kg.Formal Name: octahydro-3S-methyl-8aS-methylene-5-(1-methylethylidene)-6H-3aS,6-epoxyazulen-6R-ol. CAS Number: 24063-71-6. Synonyms: (+)-Isocurcumenol. Molecular Formula: C15H22O2. Formula Weight: 234.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml, Ethanol: slightly soluble. SMILES: C=C([C@@]1([H])[C@]([C@@H](C)CC1)(O2)C/3)C[C@]2(O)C3=C(C)/C. InChi Code: InChI=1S/C15H22O2/c1-9(2)13-8-14-11(4)5-6-12(14)10(3)7-15(13,16)17-14/h11-12,16H,3,5-8H2,1-2,4H3/t11-,12-,14-,15+/m0/s1. InChi Key: DEBDFZGNZTYPMF-NZBPQXDJSA-N. Origin: Plant/Curcuma phaeocaulis.