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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
IR 783 is a heptamethine cyanine fluorescent probe for in vivo imaging of tumor cells. It... more
Product information "IR 783"
IR 783 is a heptamethine cyanine fluorescent probe for in vivo imaging of tumor cells. It displays excitation/emission maxima of 633/780 nm, respectively. IR 783 is transported into tumor cells, an effect that can be blocked by the organic anion transporting polypeptide (OATP) inhibitor sulfobromophthalein (bromosulfalein, Cay-21058). In vivo, IR 783 (11.25 mg/kg) preferentially accumulates in tumor tissue in an ACHN kidney cancer mouse xenograft model. It has been conjugated to polyethylenimines for tumor-specific gene delivery.Formal Name: 2-[2-[2-chloro-3-[2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium, inner salt, monosodium salt. CAS Number: 115970-66-6. Molecular Formula: C38H46ClN2O6S2 . Na. Formula Weight: 749.4. Purity: >95%. Emission: 780 nm. Excitation: 633 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 786 nm. SMILES: ClC1=C(CCC/C1=C\C=C2C(C)(C)C3=CC=CC=C3N\2CCCCS([O-])(=O)=O)/C=C/C4=[N+](CCCCS([O-])(=O)=O)C5=CC=CC=C5C4(C)C.[Na+]. InChi Code: InChI=1S/C38H47ClN2O6S2.Na/c1-37(2)30-16-5-7-18-32(30)40(24-9-11-26-48(42,43)44)34(37)22-20-28-14-13-15-29(36(28)39)21-23-35-38(3,4)31-17-6-8-19-33(31)41(35)25-10-12-27-49(45,46)47,/h5-8,16-23H,9-15,24-27H2,1-4H3,(H-,42,43,44,45,46,47),/q,+1/p-1. InChi Key: QQIQAVJARACLHE-UHFFFAOYSA-M.
Keywords: | 2-[2-[2-chloro-3-[2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium, inner salt, monosodium salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 31633 |
Properties
Application: | Fluorescent probe, In vivo tumor cell imaging |
MW: | 749.4 D |
Formula: | C38H46ClN2O6S2 . Na |
Purity: | >95% |
Format: | Crystalline Solid |
Database Information
CAS : | 115970-66-6| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
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H Phrases: | H315, H319, H335 |
P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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