gamma-CEHC

The major tocopherol obtained from natural dietary sources is gamma-tocopherol, whereas alpha-tocopherol is the form of Vitamin E typically obtained from synthetic supplements. gamma-CEHC is a beta-oxidized metabolite of dietary gamma-tocopherol that functions as a natriuretic hormone. It was initially purified and characterized from the urine of uremic patients, but it has since been found in urine from both control patients and those with congestive heart failure. gamma-CEHC is also anti-inflammatory, reducing 8-isoprostane and inflammatory eicosanoid synthesis in rat models.Formal Name: 3,4-dihydro-6-hydroxy-2,7,8-trimethyl-2H-1-benzopyran-2-propanoic acid. CAS Number: 178167-75-4. Synonyms: gamma-Tocopherol Metabolite, GTM, 2,7,8-trimethyl-2-(beta-Carboxy-Ethyl)-6-Hydroxychroman. Molecular Formula: C15H20O4. Formula Weight: 264.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (7.2): 0.1 mg/ml. lambdamax: 296 nm. SMILES: OC(=O)CCC1(C)CCc2cc(O)c(C)c(C)c2O1. InChi Code: InChI=1S/C15H20O4/c1-9-10(2)14-11(8-12(9)16)4-6-15(3,19-14)7-5-13(17)18/h8,16H,4-7H2,1-3H3,(H,17,18). InChi Key: VMJQLPNCUPGMNQ-UHFFFAOYSA-N.