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Fingolimod, Hydrochloride Salt (FTY-720A, FTY720, Gilenia, Gilenya, CAS 162359-56-0), >99%
Product information "Fingolimod, Hydrochloride Salt (FTY-720A, FTY720, Gilenia, Gilenya, CAS 162359-56-0), >99%"
Soluble in DMSO at 100 mg/mL, soluble in ethanol at 100 mg/mL, very poorly soluble in water. Up to 25 µL of a solution of 13.8 mg/mL (40 mM) fingolimod-HCl in 100% DMSO can be diluted into 5 mL of plain water without precipitation, giving a final concentration of 200 µM. In contrast, even a 1-to-1000 dilution of the same 13.8 mg/mL DMSO stock solution into a 10 mM phosphate-buffered saline at pH 7 results in a precipitate. Thus, fingolimod-HCl solubility in PBS is likely to be well below 100 µM, perhaps as low as 1-10 µg/mL. Either DMSO, ethanol or plain water should be used as the solvent until the final dilution is made into culture medium. Buffers, serum, or other additives may increase or decrease the aqueous solubility.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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