Erucin

Erucin is an isothiocyanate derived from glucoerucin, a glucosinolate predominant in arugula (Eruca sativa Mill.) and other cruciferous vegetables. At 2.5-5 µM erucin can induce significant neuroprotective and antioxidant effects, increasing both total glutathione levels and total antioxidant capacity at the cytosolic level in dopaminergic-like neuroblastoma SH-SY5Y cells. Growth inhibition, cell cycle regulation, apoptosis, and induction of detoxification enzymes have all been reported from use of erucin in prostate, lung, liver, and colon cancer cells.Formal Name: 1-isothiocyanato-4-(methylthio)-butane. CAS Number: 4430-36-8. Molecular Formula: C6H11NS2. Formula Weight: 161.3. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 12 mg/ml, DMSO: 14 mg/ml, Ethanol: 16 mg/ml, Ethanol:PBS (pH7.2)(1:50): 0.02 mg/ml. lambdamax: 244 nm. SMILES: CSCCCCN=C=S. InChi Code: InChI=1S/C6H11NS2/c1-9-5-3-2-4-7-6-8/h2-5H2,1H3. InChi Key: IHQDGXUYTSZGOG-UHFFFAOYSA-N.