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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CDX-E0128-M010 | 10 mg | - | - |
3 - 9 business days* |
145.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
White to off-white powder. Soluble in ethanol (10 mg/ml), DMF (20 mg/ml), DMSO (20 mg/ml) or... more
Product information "(-)-Epigallocatechin gallate"
White to off-white powder. Soluble in ethanol (10 mg/ml), DMF (20 mg/ml), DMSO (20 mg/ml) or water (10 mg/ml). Chemical. CAS: 989-51-5. Formula: C22H18O11. MW: 458.37. (-)-Epigallocatechin gallate (EGCG), an antioxidant and anti-inflammatory polyphenol flavonoid exerts antitumor properties by inhibiting telomerase and DNA methyltransferase activity. EGCG inhibits the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and reduces the invasiveness. EGCG blocks the activation of epidermal growth factor (EGF) receptors and human epidermal growth factor receptor-2 (HER-2). Regulates cancer cell growth, proliferation, transformation, survival, angiogenesis, apoptosis, invasion and metastasis. EGCG increases bone mineral density and reduces bone resorption. EGCG inhibits osteoclastogenesis by inhibiting receptor activator of nuclear factor kappaB ligand (RANKL) induced nuclear factor kappa B (NF-kappaB) transcriptional activity. EGCG has neuroprotective and anti-aging property and increases myogenic differentiation. EGCG inhibits fatty acid synthase and glutamate dehydrogenase activity. EGCG has preventive cardiovascular and metabolic (obesity, insulin resistance, hypertension and hypercholesterolemia) effects and in vivo, EGCG reduces food intake and body weight, serum levels of insulin, leptin, testosterone and growth hormone.
Keywords: | (-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate, Epigallocatechin-3-gallate, EGCG, CCRIS 3729, Teavigo, NVP-XAA 723 |
Supplier: | Chemodex |
Supplier-Nr: | E0128 |
Properties
Host: | Plant |
MW: | 458,37 D |
Formula: | C22H18O11 |
Purity: | > 98% (HPLC) |
Format: | Solid |
Database Information
CAS : | 989-51-5| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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