(E)-4-Hydroxytamoxifen
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Larger quantity required? Request bulk
(E)-4-Hydroxytamoxifen is the less active isomer of 4-hydroxytamoxifen. 4-Hydroxytamoxifen is the... more
Product information "(E)-4-Hydroxytamoxifen"
(E)-4-Hydroxytamoxifen is the less active isomer of 4-hydroxytamoxifen. 4-Hydroxytamoxifen is the active metabolite of tamoxifen, a selective estrogen receptor modulator (SERM) that acts as an agonist or antagonist in various tissues. 4-Hydroxytamoxifen exhibits anticancer chemotherapeutic activity, inducing autophagy and vacuole formation as well as KRAS degradation in various cancer cell lines. In cardiac myocytes, 4-hydroxytamoxifen decreases Ca2+ amplitude, slowing relaxation and decreasing contractility.
| Supplier: | LKT Laboratories |
| Supplier-Nr: | H9712 |
Properties
| Application: | Metabolic studies |
| MW: | 387,51 D |
Database Information
| CAS : | 174592-47-3| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H361, H302+H312+H332 |
| P Phrases: | P201, P202, P261, P264, P270, P271, P281, P301, P302, P304, P308, P312, P313, P322, P330, P340, P352, P363, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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