Diroximel Fumarate

Diroximel fumarate is a prodrug form of monomethyl fumarate (Cay-27813). It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.Formal Name: (2E)-butenedioic acid, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester. CAS Number: 1577222-14-0. Synonyms: BIIB098. Molecular Formula: C11H13NO6. Formula Weight: 255.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10mg/mL, DMSO: 10mg/mL, DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL. SMILES: COC(/C=C/C(OCCN1C(CCC1=O)=O)=O)=O. InChi Code: InChI=1S/C11H13NO6/c1-17-10(15)4-5-11(16)18-7-6-12-8(13)2-3-9(12)14/h4-5H,2-3,6-7H2,1H3/b5-4+. InChi Key: YIMYDTCOUQIDMT-SNAWJCMRSA-N.